Bitchin'!
Okay, a quick lesson for all you chickenheads out there. I pulled some hair out figuring this out but its easy once you get the hang of it.
Powerpuff Girls (manholes): Stay at the center of the screen. Blitz for a Powerpuff girl once she pops up, whack, and run back to center while she's still reeling. Repeat.
Powerpuff Girls (Aerial): Strafe the formation repeatedly up and down, up and down. Keep an eye on those laser blasts tho, and dont run into them.
Death Knights: Come up from below and to one side swinging. Try and get it so you bag both but avoid if you can't and the other's within his swinging distance. Timing is everything so it's more speed than strategy, really.
Powerpuff Girls (Final): Just keep at one of your choice, but dont take up the opportunity to repeatedly hammer one that just goes right up to you. While whaling away, keep an eye on the other two so they don't shoot at you from a distance though.
Death Adder: Same as the knights, you have to come at an angle and time it VERY exactly. If you screw up and he axes you, you have a split second to hit back before he blows up the whole screen on you so USE IT. Runnin dosent do shit. The Powerpuff Ghouls take too many brain cells to keep track of so just IGNORE THEM.
I hope this helps someone. Great game, Tom, you've outdone yourself again.